Avian influenza refers to infection of birds with avian influenza Type A viruses. These viruses occur naturally among wild aquatic birds worldwide and can infect domestic poultry and other bird and animal species. Wild aquatic birds can be infected with avian influenza A viruses in their intestines and respiratory tract, but usually do not get sick. However, avian influenza A viruses are very contagious among birds and some of these viruses can sicken and even kill certain domesticated bird species including chickens, ducks, and turkeys.
Infected birds can shed avian influenza A viruses in their saliva, nasal secretions, and feces. Susceptible birds become infected when they have contact with the virus as it is shed by infected birds. They also can become infected through contact with surfaces that are contaminated with virus from infected birds.
Infection of poultry with LPAI viruses may cause no disease or mild illness and may only cause mild signs (such as ruffled feathers and a drop in egg production) and may not be detected. Infection of poultry with HPAI viruses can cause severe disease with high mortality. Both HPAI and LPAI viruses can spread rapidly through flocks of poultry. HPAI virus infection in poultry (such as with HPAI H5 or HPAI H7 viruses) can cause disease that affects multiple internal organs with mortality up to 90% to 100%, often within 48 hours. Some ducks can be infected without any signs of illness.