February 13, 2025

Evaluation of Peroxides and Chlorine Oxides as Disinfectants for Chemical Sterilization of Gnotobiotic Rodent Isolators

Executive Summary

Study on the Effect of Accelerated Hydrogen Peroxide in Rodent Isolators

Title: Evaluation of Peroxides and Chlorine Oxides as Disinfectants for Chemical Sterilization of Gnotobiotic Rodent Isolators
Authors: LaTisha V Moody, Yukiko Miyamoto, Jonathan Ang, Philip J Richter, Lars Eckmann
Published: Journal of the American Association for Laboratory Animal Science, Vol 58, No 5, Sept. 2019, pp 558-568

Key Findings:

Rescue (AHP) caused significant damage to acrylic surfaces, leaving a thick surface deposit that could not be removed.
Rescue was also found to be a less effective biocide than many of the other disinfectants tested.
It also damaged vinyl surfaces, leaving permanent deposits that remained after cleaning.

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