Hydrogen Peroxide vs. Quaternary Ammonium Compounds

A Comparison Study of Disinfectant Cleaners based on Hydrogen Peroxide or Quaternary Ammonium Compounds

Executive Summary

Executive Summary:

  • The paper compares the efficacy of hydrogen peroxide-based formulations to quaternary ammonium compounds (QACs) in hard-surface antimicrobial applications.
  • The study used the AOAC Use Dilution test to evaluate microbiological efficacy, surface cleaning, metal corrosion, and environmental impact.
  • Two hydrogen peroxide-based formulations, Stabilized Hydrogen Peroxide (SHP) and Accelerated Hydrogen Peroxide (AHP), were compared to a quaternary ammonia disinfectant against two organisms: Pseudomonas aeruginosa and Staphylococcus aureus.
  • The test was conducted under increasingly difficult conditions: deionized water alone, deionized water plus 5% soil, and 400 ppm hard water.
  • The Quaternary Ammonia Formulation tested was found to be more efficacious against Pseudomonas aeruginosa than the hydrogen peroxide solution.
  • The H2O2 solution allowed significant growth of Staphylococcus aureus even at twice the recommended concentration under all test conditions.
  • The AHP product with 7% hydrogen peroxide was found to be as efficacious as the Quaternary Ammonia Formulation S-21F but requires four times the amount of active product.
  • Estimated time to read: 5-7 minutes.

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